Overview
| Product name | Recombinant Human Neutrophil cytosol factor 1/NCF1 Protein |
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| Catalog No. | RP03285 |
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| Description | Recombinant Human Neutrophil cytosol factor 1/NCF1 Protein is produced by E.coli expression system. The target protein is expressed with sequence (Met1-Val390) of human Neutrophil cytosol factor 1/NCF1 (Accession #P14598) fused with His tag at the C-terminus. |
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| Purity | > 95% by SDS-PAGE. |
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| Endotoxin | < 1.0 EU/μg of the protein by LAL method. |
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| Formulation | Lyophilized from a 0.22 μm filtered solution of 20 mM Tris-HCl, 100 mM NaCl, 1 mM DTT, pH 8.0. Contact us for customized product form or formulation. |
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| Species | Human |
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| Calculated MW | 45.6 kDa |
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Background
NCF1 is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This protein is essential for activation of the NADPH oxidase complex, which is essential for superoxide production. It cooperates with NCF2 to form a core association in the complex, interacting with NCF4, CYBB and CYBA. Mutations in the NCF1 gene have been associated with chronic granulomatous disease.
Product information
| Synonym | NCF1; NOXO2; SH3PXD1A; NCF-47K; NCF-1; p47-phox; Nox organizer 2; Neutrophil cytosol factor 1; Neutrophil NADPH oxidase factor 1; 47 kDa neutrophil oxidase factor; 47 kDa autosomal chronic granulomatous disease protein |
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| Expression Host | E.coli |
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| Tag | C-His |
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| Swiss-Prot | |
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| Gene ID | |
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Usage guide
| Storage | Store at -20℃. Store the lyophilized protein at -20℃ to -80℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
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| Reconstitution | Please contact us for reconstitution instructions. |
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* For research use only. Not for therapeutic or diagnostic purposes.
