Overview
Product name | Recombinant Human PG II(PGC) Protein |
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Catalog No. | RP01735 |
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Description | Recombinant Human PG II(PGC) Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Ala388) of human PG II(PGC) (Accession #NP_002621.1) fused with a 6×His tag at the C-terminus. |
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Purity | > 97% by SDS-PAGE. |
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Endotoxin | < 0.01EU/μg |
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Formulation | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. |
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Species | Human |
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Calculated MW | 43.27 kDa |
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Background
Pepsinogen C, also known as PGC, is an aspartic proteinase that belongs to the peptidase family A1. Pepsinogen C is synthesized in the gastric mucosa as inactive precursors, known as zymogens. Pepsinogen C contains a prosegment that serves to stabilize the inactive form and prevent entry of the substrate to the active site. At low PH conditions, Pepsinogen C undergoes conversion into active enzyme.
Product information
Synonym | PEPC; PGII; PG II(PGC) |
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Expression Host | HEK293 cells |
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Tag | C-6His |
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Swiss-Prot | |
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Gene ID | |
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Usage guide
Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
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Reconstitution | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.