제품 > 항체 > 단일클론항체(mAb)

Pepsinogen II (PG II) Rabbit mAb (A22282)

Datasheet

Tested applications:WBIHC-PIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIPCUT&TagmeRIPInhibitionReactivity:Human, Mouse, Rat

ABclonal:Immunohistochemistry - Pepsinogen II (PG II) Rabbit mAb (A22282)

Immunohistochemistry analysis of paraffin-embedded Human stomach using Pepsinogen II (PG II) Rabbit mAb (A22282) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate Bufferr (pH 6.0) prior to IHC staining.

ABclonal:Immunohistochemistry - Pepsinogen II (PG II) Rabbit mAb (A22282)

Immunohistochemistry analysis of paraffin-embedded Mouse stomach using Pepsinogen II (PG II) Rabbit mAb (A22282) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate Bufferr (pH 6.0) prior to IHC staining.

ABclonal:Immunohistochemistry - Pepsinogen II (PG II) Rabbit mAb (A22282)

Immunohistochemistry analysis of paraffin-embedded Rat stomach using Pepsinogen II (PG II) Rabbit mAb (A22282) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate Bufferr (pH 6.0) prior to IHC staining.

Overview

Product namePepsinogen II (PG II) Rabbit mAb
Catalog No.A22282
Host speciesRabbit
Purification methodAffinity purification
IsotypeIgG
CloneNo.ARC57717
This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-388 of human Pepsinogen II (PG II) (NP_002621.1).
SequenceMKWMVVVLVCLQLLEAAVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMAYMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQSQACTSHSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQGSSGGAVVFGGVDSSLYTGQIYWAPVTQELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQYMSALLQATGAQEDEYGQFLVNCNSIQNLPSLTFIINGVEFPLPPSSYILSNNGYCTVGVEPTYLSSQNGQPLWILGDVFLRSYYSVYDLGNNRVGFATAA
Gene ID
Swiss Prot
SynonymsPEPC; PGII; Pepsinogen II (PG II)
Calculated MW42kDa
Observed MWRefer to figures
ReactivityHuman, Mouse, Rat
Tested applicationsWBIHC-PIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIPCUT&TagmeRIPInhibition
Recommended dilution
  • IHC-P 1:50 - 1:200
Storage bufferStore at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Key applicationImmunohistochemistry    
Positive samples
Cellular locationSecreted.

Documents

Certificate of Compliance

To download a Certificate of Compliance, please enter your Lot number below:

Lot number

ABclonal:Immunohistochemistry - Pepsinogen II (PG II) Rabbit mAb (A22282)}

Immunohistochemistry - Pepsinogen II (PG II) Rabbit mAb (A22282)

Immunohistochemistry analysis of paraffin-embedded Human stomach using Pepsinogen II (PG II) Rabbit mAb (A22282) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate Bufferr (pH 6.0) prior to IHC staining.
ABclonal:Immunohistochemistry - Pepsinogen II (PG II) Rabbit mAb (A22282)}

Immunohistochemistry - Pepsinogen II (PG II) Rabbit mAb (A22282)

Immunohistochemistry analysis of paraffin-embedded Mouse stomach using Pepsinogen II (PG II) Rabbit mAb (A22282) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate Bufferr (pH 6.0) prior to IHC staining.
ABclonal:Immunohistochemistry - Pepsinogen II (PG II) Rabbit mAb (A22282)}

Immunohistochemistry - Pepsinogen II (PG II) Rabbit mAb (A22282)

Immunohistochemistry analysis of paraffin-embedded Rat stomach using Pepsinogen II (PG II) Rabbit mAb (A22282) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate Bufferr (pH 6.0) prior to IHC staining.

* For research use only. Not for therapeutic or diagnostic purposes.

항체 (2)

제품 (2)

재조합 단백질 (1)

Secondary Antibodies (26)