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Recombinant Human VAMP-B/VAMP-C Protein (RP02136)

Datasheet

Overview

Product nameRecombinant Human VAMP-B/VAMP-C Protein
Catalog No.RP02136
DescriptionRecombinant Human VAMP-B/VAMP-C Protein is produced by E.coli expression system. The target protein is expressed with sequence (Ala2-Pro132) of human VAMPB (Accession #O95292) fused with a 6xHis tag at the C- terminus.
Purity> 90% by SDS-PAGE.
Endotoxin< 1 EU/μg of the protein by LAL method.
FormulationLyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
SpeciesHuman
Calculated MW16 kDa
vesicle-associated membrane protein-associated protein B/C (VAPB) is presents in mitochondria-associated membranes that are endoplasmic reticulum membrane regions closely apposed to the outer mitochondrial membrane. It can form homodimer, and heterodimer with VAPA. It also interacts with VAMP1, VAMP2, HCV NS5A, NS5B, ZFYVE27 and RMDN3. VAPB participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. It is involved in cellular calcium homeostasis regulation.
SynonymVAPB; ALS8; VAMP-B; VAP-B
Expression HostE. coli
TagC-His
Swiss-Prot
Gene ID
StorageStore at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
ReconstitutionCentrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

* For research use only. Not for therapeutic or diagnostic purposes.

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