Overview
Product name | Recombinant Human XPNPEP3 Protein |
---|
Catalog No. | RP03207LQ |
---|
Description | Recombinant Human XPNPEP3 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Ser507) of Human XPNPEP3 (Accession #NP_071381.1) fused with a 6His tag at the N-terminus, 6His tag at the C-terminus. |
---|
Purity | > 95% by SDS-PAGE. |
---|
Endotoxin | < 1 EU/μg of the protein by LAL method. |
---|
Formulation | Supplied as a 0.22 μm filtered solution in 25mM Tris-HCl, 1mM DTT, pH 7.3. Contact us for customized product form or formulation. |
---|
Species | Human |
---|
Calculated MW | 60.2 KDa |
---|
Background
Probable Xaa-Pro Aminopeptidase 3 (XPNPEP3) is a member of the peptidase M24B family. XPNPEP3 has two isoforms and both are widely expressed. XPNPEP3 is localized in the Mitochondrion. XPNPEP3 catalyzes the release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide. Defects in XPNPEP3 are the cause of nephronophthisis-like nephropathy type 1 which is a disorder with features of nephronophthisis, a cystic kidney disease leading to end-stage renal failure.
Product information
Synonym | Probable Xaa-Pro Aminopeptidase 3; X-Pro Aminopeptidase 3; Aminopeptidase P3; APP3; XPNPEP3 |
---|
Expression Host | E. coli |
---|
Tag | N, C-6His |
---|
Swiss-Prot | |
---|
Gene ID | |
---|
Usage guide
Storage | Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles. |
---|
* For research use only. Not for therapeutic or diagnostic purposes.