| Product name | Rabbit anti-Human IL-12/IL-23 p40 mAb |
|---|---|
| Catalog No. | RM17932 |
| Catagory | Elisa Antibody Kit |
| Application | ELISA |
| Description | This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. |
| Immunogen | Recombinant Human IL-12/IL-23 p40 Protein |
| Purirty | Affinity purification |
| Ig Type | Rabbit IgG |
| Formulation | Supplied as a 0.2um filtered solution in PBS with 0.05%ProClin 300, PH 7.4. |
| CrossReactivity | No cross-reactivity in ELISA assay withrecombinant Mouse IFN-γ、Mouse IFN-β、Mouse IL-20、Mouse IL-22、Mouse IL-24、Human IL-10 Has cross-reactivity in ELISA with Rat IL-10 |
| Storage | Store at -20℃. Avoid repeated freeze-thaw cycles. |
Human IL-12/IL-23 p40 Sandwich ELISA
| Recommended Concentration | Sample | ||
|---|---|---|---|
| ELISA | Capture | 1-4ug/mL | Rabbit anti-Human IL-12/IL-23 p40 mAb(Cat. No.RM17931) |
| Detection | 0.05-0.2ug/mL | Rabbit anti-Human IL-12/IL-23 p40 mAb(Cat. No.RM17932) | |
| Standard | 15.62-1000pg/mL | RecombinantHuman IL-12/IL-23 p40 Protein |
