| Product name | Rabbit anti-Human Tissue Factor mAb (DET) |
|---|---|
| Catalog No. | RMK0412 |
| Catagory | Elisa Antibody Kit |
| Application | multiplex assay |
| Description | This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces, for example, on monocytes. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. Platelets and monocytes have been shown to express this coagulation factor under procoagulatory and proinflammatory stimuli, and a major role in HIV-associated coagulopathy has been described. Platelet-dependent monocyte expression of coagulation factor III has been described to be associated with Coronavirus Disease 2019 (COVID-19) severity and mortality. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants. |
| Immunogen | Recombinant Human Tissue Factor Protein |
| Purirty | Affinity purification |
| Ig Type | Rabbit IgG |
| Formulation | Supplied as a 0.2um filtered solution in PBS, PH 7.4 containing Human Tissue Factor Antibody |
| CrossReactivity | / |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. Preservative：0.05%ProClin 300. Avoid repeated freeze-thaw cycles. |
Human Tissue Factor multiplex assay
| Recommended Concentration | Sample | |
|---|---|---|
| Multiplex Capture | 3-20ug/mL | Rabbit anti-Human Tissue Factor mAb(Cat. No.RMK0412) |
| Multiplex Detection | 0.017-2ug/mL | Rabbit anti-Human Tissue Factor mAb(Cat. No.RMK0412) |
| Standard | 6.86-5000pg/mL | Recombinant Human Tissue Factor Protein |
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