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Biotinylated Recombinant Human FLT-3/FLK-2/CD135 Protein (RP00459BLQ)

Datasheet

Overview

Product nameBiotinylated Recombinant Human FLT-3/FLK-2/CD135 Protein
Catalog No.RP00459BLQ
DescriptionBiotinylated Recombinant Human FLT3/Flk-2 Protein is produced by CHO cells expression system. The target protein is expressed with sequence (Asn27-Asn541) of Human FLT3/Flk-2 (Accession #P36888-1) fused with a C-His&Avi tag at the C-terminus.
Purity> 95% by SDS-PAGE;> 95% by HPLC
Endotoxin< 1 EU/μg of the protein by LAL method
FormulationSupplied as 0.22 μm filtered solution in PBS (pH 7.4).
SpeciesHuman
Calculated MW61.20 kDa
The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and Stk-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes KIT, the receptor for SCF and FMS, the receptor for M-CSF. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1.
SynonymCD135; FLK2; STK-1; FLT-3
Expression HostCHO cells
TagC-His&Avi
Swiss-Prot
Gene ID
StorageStore at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles.

* For research use only. Not for therapeutic or diagnostic purposes.

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