Overview
| Product name | Recombinant Human BMP-4 (E399D) Protein |
|---|
| Catalog No. | RP02512S |
|---|
| Description | Recombinant Human BMP-4 (E399D) Protein is produced by E.coli expression system. The target protein is expressed with sequence (Ser293-Arg408 (E399D)) of human BMP-4 (Accession #P12644) fused with No tag. |
|---|
| Bio-Activity | Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells.The ED50 for this effect is 30.3-121.2 ng/mL, corresponding to a specific activity of 8.25×103~3.30×104 units/mg.
|
|---|
| Purity | > 95% by SDS-PAGE. |
|---|
| Endotoxin | < 1.0 EU/μg of the protein by LAL method. |
|---|
| Formulation | Lyophilized from a 0.22 μm filtered solution of 0.1% TFA, 30% Acetonitrile. Contact us for customized product form or formulation. |
|---|
| Species | Human |
|---|
| Calculated MW | 13.25 kDa |
|---|
Background
Bone morphogenetic protein 4 is a protein that in humans is encoded by BMP4 gene. BMP4 is found on chromosome 14q22-q23. BMP4 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. BMP4 is highly conserved evolutionarily. BMP4 is found in early embryonic development in the ventral marginal zone and in the eye, heart blood and otic vesicle.
Product information
| Synonym | BMP-4; BMP4; BMP2B; BMP2B1; MCOPS6; OFC11; ZYME |
|---|
| Expression Host | E.coli |
|---|
| Tag | No tag |
|---|
| Swiss-Prot | |
|---|
| Gene ID | |
|---|
Usage guide
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
|---|
| Reconstitution | Reconstituted with 4mM HCl to 0.25mg/mL. |
|---|
* For research use only. Not for therapeutic or diagnostic purposes.
