Overview
Product name | Recombinant Human Basigin EMMPRIN/CD147 Protein |
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Catalog No. | RP00608 |
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Description | Recombinant Human EMMPRIN/CD147 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala22-His205) of Human EMMPRIN/CD147 (Accession #Q54A51) fused with a C-His tag at the C-terminus. |
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Purity | > 95% by SDS-PAGE;> 95% by HPLC |
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Endotoxin | < 1 EU/μg of the protein by LAL method |
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Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
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Species | Human |
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Calculated MW | 21.2 kDa |
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Background
CD147, also known as extracellular matrix metalloproteinase inducer (EMMPRIN) or basigin, is expressed in a variety of cell types. It is involved in the regulation of extracellular matrix (ECM) remodeling during physiological and pathological processes including wound healing, inflammatory diseases, and cancer. CD147 is a diagnostic and therapeutic target in cancer and inflammatory diseases, either directly or indirectly, by targeting CD147 partners.
Product information
Synonym | Basigin; BSG; CD147; 5F7; M6; OK; TCSF |
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Expression Host | HEK293 cells |
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Tag | C-His |
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Swiss-Prot | |
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Gene ID | |
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Usage guide
Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
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Reconstitution | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.