Recombinant Human Calumenin/CALU Protein (RP03261)

Overview

Product name	Recombinant Human Calumenin/CALU Protein
Catalog No.	RP03261
Description	Recombinant Human Calumenin/CALU Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Ala413) of Human Calumenin/CALU (Accession #P27797) fused with His tag at the C-terminus.
Purity	≥ 95% by SDS-PAGE; ≥ 90% by SEC-HPLC
Endotoxin	< 1.0 EU/μg of the protein by LAL method.
Formulation	Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Species	Human
Calculated MW	47.4 kDa

Calreticulin is a calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Calreticulin reduces the binding of androgen receptor to its hormone-responsive DNA element and inhibits androgen receptor and retinoic acid receptor transcriptional activities in vivo, as well as retinoic acid-induced neuronal differentiation.

Product information

Synonym	Calreticulin; CRP55; ERp60; HACBP; grp60; CALR; CRTC; cC1qR; HEL-S-99n; SSA
Expression Host	HEK293 cells
Tag	C-His
Swiss-Prot
Gene ID

Usage guide

Storage	Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution	Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

* For research use only. Not for therapeutic or diagnostic purposes.