Overview
| Product name | Recombinant Human DHLAG/CD74 Protein |
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| Catalog No. | RP02736 |
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| Description | Recombinant Human DHLAG/CD74 Protein is produced by Expi293 cells expression system. The target protein is expressed with sequence (Gln73-Met232) of Human DHLAG/CD74 (Accession #NP_004346.1) fused with His tag at the N-terminus. |
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| Purity | > 95% as determined by Tris-Bis PAGE |
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| Endotoxin | Less than 1EU per μg by the LAL method. |
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| Species | Human |
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| Calculated MW | 19.1 kDa |
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Background
CD74 (invariant MHC class II) regulates protein trafficking and is a receptor for macrophage migration inhibitory factor (MIF) and d-dopachrome tautomerase (d-DT/MIF-2). CD74 expression is increased in tubular cells and/or glomerular podocytes and parietal cells in human metabolic nephropathies, polycystic kidney disease, graft rejection and kidney cancer and in experimental diabetic nephropathy and glomerulonephritis.
Product information
| Synonym | CD74; Ii; DHLAG; HLADG; Ia-GAMMA; p33; CLIP; INVG34; Ia-GAMMA ; II |
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| Expression Host | HEK293 cells |
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| Tag | N-His |
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| Swiss-Prot | |
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| Gene ID | |
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Usage guide
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
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| Reconstitution | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.
