Overview
| Product name | Recombinant Human Fc-gamma RIII alpha/FCGR3A/CD16a (F176V) Protein |
|---|
| Catalog No. | RP00478 |
|---|
| Description | Recombinant Human Fc-gamma RIII alpha/FCGR3A /CD16a (F176V) Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly17-Gln208(F176V)) of Human Fc-gamma RIII alpha/FCGR3A /CD16a (F176V) (Accession #AAH17865) fused with a C-His&Avi tag at the C-terminus. |
|---|
| Purity | > 95% by SDS-PAGE；> 95% by HPLC |
|---|
| Endotoxin | < 1 EU/μg of the protein by LAL method |
|---|
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
|---|
| Species | Human |
|---|
| Calculated MW | 24.7 kDa |
|---|
Background
Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.
Product information
| Synonym | Fc gamma RIIIA; FCGR3; FCGR3A; FCGRIII; FcgRIIIA; FcR-10; CD16A; FCG3; IGFR3; FcRIIIa; FcRIII; CD16; IMD20 |
|---|
| Expression Host | HEK293 cells |
|---|
| Tag | C-His&Avi |
|---|
| Swiss-Prot | |
|---|
| Gene ID | |
|---|
Usage guide
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
|---|
| Reconstitution | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
|---|
* For research use only. Not for therapeutic or diagnostic purposes.
