Overview
| Product name | Recombinant Human Ferritin heavy chain/FTH1 Protein |
|---|
| Catalog No. | RP00631 |
|---|
| Description | Recombinant Human Ferritin heavy chain/FTH1 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Ser183) of human Ferritin heavy chain/FTH1 (Accession #P02794). |
|---|
| Purity | > 95% by SDS-PAGE. |
|---|
| Endotoxin | < 1 EU/μg of the protein by LAL method. |
|---|
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.Contact us for customized product form or formulation. |
|---|
| Species | Human |
|---|
| Calculated MW | 21.22 kDa |
|---|
Background
Ferritin heavy polypeptide 1(FTH1), is a ubiquitous intracellular protein which stores iron in a soluble, non-toxic, readily available form. FTH1 has ferroxidase activity and is important for iron homeostasis. Iron is takenup in the ferrous form and deposited as ferric hydroxides after oxidation. Ferritin is composed of 24 subunits ofthe light and heavy ferritin chains. It plays a role in delivery of iron to cells and mediates iron uptake in capsulecells of the developing kidney. Variation of ferritin subunit composition may affect iron absorption and releasein different tissues. Deficiency of ferritin proteins may cause several neurodegenerative diseases. Almost allliving organisms can produce this protein, including algae, bacteria, higher plants, and animals.
Product information
| Synonym | FHC; FTH; FTHL6; HFE5; PIG15; PLIF; Ferritin; FTH1 |
|---|
| Expression Host | E. coli |
|---|
| Tag | No tag |
|---|
| Swiss-Prot | |
|---|
| Gene ID | |
|---|
Usage guide
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
|---|
| Reconstitution | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
|---|
* For research use only. Not for therapeutic or diagnostic purposes.
