FITC-Labeled Recombinant Human B7-H3/CD276 Protein (RP00635FLQ)

Overview

Product name	FITC-Labeled Recombinant Human B7-H3/CD276 Protein
Catalog No.	RP00635FLQ
Description	FITC-Labeled Recombinant Human B7-H3/CD276 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu29-Pro245) of Human B7-H3/CD276 (Accession #Q5ZPR3-2) fused with a C-hFc tag at the C-terminus.
Purity	> 95% by SDS-PAGE
Endotoxin	< 1 EU/μg of the protein by LAL method
Formulation	Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Species	Human
Calculated MW	50.1 kDa

B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig?B7?H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction.

Product information

Synonym	B7H3; B7-H3; CD276; PSEC0249; UNQ309; PRO352; B7 homolog 3; CD276
Expression Host	HEK293 cells
Tag	C-hFc
Swiss-Prot
Gene ID

Usage guide

Storage	Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles.

* For research use only. Not for therapeutic or diagnostic purposes.