Overview
| Product name | Recombinant Human Glucose-6-phosphate 1-dehydrogenase/G6PD Protein |
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| Catalog No. | RP02937LQ |
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| Description | Recombinant Human Glucose-6-phosphate 1-dehydrogenase/G6PD Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala2-Leu515) of human Glucose-6-phosphate 1-dehydrogenase/G6PD (Accession #NP_001035810.1) fused with 6×His tag at the C-terminus. |
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| Purity | > 95 % as determined by SDS-PAGE |
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| Endotoxin | <1EU/μg |
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| Formulation | Supplied as a 0.22 μm filtered solution in PBS, pH 7.4. |
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| Species | Human |
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| Calculated MW | 60.2 kDa |
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Background
Glucose-6-Phosphate 1-Dehydrogenase (G6PD) is a cytosolic enzyme that belongs to the glucose-6-phosphate dehydrogenase family. G6PD participates in the pentose phosphate pathway that supplies reducing energy to cells by maintaining the level of the co-enzyme nicotinamide adenine dinucleotide phosphate (NADPH). G6PD produces pentose sugars for nucleic acid synthesis and main producer of NADPH reducing power. NADPH in turn maintains the level of glutathione in these cells that helps protect the red blood cells against oxidative damage. It is notable in humans that G6PD is remarkable for its genetic diversity. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia.
Product information
| Synonym | G6PD; G6PD1; glucose-6-phosphate dehydrogenase; G6PD1 |
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| Expression Host | HEK293 cells |
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| Tag | C-His |
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| Swiss-Prot | |
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| Gene ID | |
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Usage guide
| Storage | Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.
