Recombinant Human JAM-A/F11R/CD321 Protein (RP00275)

Overview

Product name	Recombinant Human JAM-A/F11R/CD321 Protein
Catalog No.	RP00275
Description	Recombinant Human JAM-A/F11R/CD321 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ser28-Ala242) of human JAM-A (Accession #NP_058642.1) fused with a 6×His tag at the C-terminus.
Purity	> 92% by SDS-PAGE.
Endotoxin	< 0.1 EU/μg of the protein by LAL method.
Formulation	Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
Species	Human
Calculated MW	24.15 kDa

Junctional adhesion molecule A（JAM-A）which belongs to the immunoglobulin superfamily, seems to play a role in epithelial tight junction formation.JAM-A is expressed in endothelium, epithelium and leukocytes (at protein level).JAM-A contains Ig-like V-type 1 and Ig-like V-type 2 domains , the Ig-like V-type 2 domain is necessary and sufficient for interaction with integrin alpha-L/beta-2.

Product information

Synonym	F11R; CD321; JAM; JAM1; JAMA; JCAM; KAT; PAM-1
Expression Host	HEK293 cells
Tag	C-His
Swiss-Prot
Gene ID

Usage guide

Storage	Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution	Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

* For research use only. Not for therapeutic or diagnostic purposes.