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Recombinant Human LAMP-1/CD107a Protein (RP01027)

Bioactivityvalidated

Datasheet

Overview

Product nameRecombinant Human LAMP-1/CD107a Protein
Catalog No.RP01027
DescriptionRecombinant Human LAMP-1/CD107a Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala29-Met382) of human LAMP1 (Accession #NP_005552.3) fused with a 6×His tag at the C-terminus.
Bio-ActivityMeasured by its binding ability in a functional ELISA. Immobilized Human LAMP1 at 1 μg/mL (100 μL/well) can bind LAMP1 Rabbit pAb with a linear range of 1-8.5 ng/mL.
Purity> 97% by SDS-PAGE.
Endotoxin< 0.1 EU/μg of the protein by LAL method.
FormulationLyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
SpeciesHuman
Calculated MW39.23 kDa
Lysosomal associated membrane protein 1 (LAMP1), also known as CD107a, is a single-pass type I membrane protein which belongs to the LAMP family.LAMP-1 is a glycoprotein highly expressed in lysosomal membranes.This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. LAMP-1 acts as a receptor for Lassa virus protein. LAMP1 is presented on the plasma membrane during the activation of NK cells, CD8+ T cells, mast cells, basophils, monocytes, and platelets.
SynonymLAMP1; CD107a; LAMPA; LGP120; lysosomal associated membrane protein 1; CD107a; LAMPA; LGP120
Expression HostHEK293 cells
TagC-His
Swiss-Prot
Gene ID
StorageStore at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
ReconstitutionCentrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

* For research use only. Not for therapeutic or diagnostic purposes.

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