Overview
Product name | Recombinant Human LAMP-1/CD107a Protein |
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Catalog No. | RP01027 |
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Description | Recombinant Human LAMP-1/CD107a Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala29-Met382) of human LAMP1 (Accession #NP_005552.3) fused with a 6×His tag at the C-terminus. |
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Bio-Activity | Measured by its binding ability in a functional ELISA. Immobilized Human LAMP1 at 1 μg/mL (100 μL/well) can bind LAMP1 Rabbit pAb with a linear range of 1-8.5 ng/mL.
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Purity | > 97% by SDS-PAGE. |
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Endotoxin | < 0.1 EU/μg of the protein by LAL method. |
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Formulation | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation. |
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Species | Human |
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Calculated MW | 39.23 kDa |
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Background
Lysosomal associated membrane protein 1 (LAMP1), also known as CD107a, is a single-pass type I membrane protein which belongs to the LAMP family.LAMP-1 is a glycoprotein highly expressed in lysosomal membranes.This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. LAMP-1 acts as a receptor for Lassa virus protein. LAMP1 is presented on the plasma membrane during the activation of NK cells, CD8+ T cells, mast cells, basophils, monocytes, and platelets.
Product information
Synonym | LAMP1; CD107a; LAMPA; LGP120; lysosomal associated membrane protein 1; CD107a; LAMPA; LGP120 |
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Expression Host | HEK293 cells |
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Tag | C-His |
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Swiss-Prot | |
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Gene ID | |
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Usage guide
Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
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Reconstitution | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.