Overview
Product name | Recombinant Human PSD-95/DLG4 Protein |
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Catalog No. | RP01106 |
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Description | Recombinant Human PSD-95/DLG4 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Leu724) of human PSD-95/DLG4 (Accession #P78352) fused with a 6×His tag at the N-terminus. |
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Purity | > 95% by SDS-PAGE. |
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Endotoxin | < 1.0 EU/μg of the protein by LAL method. |
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Formulation | Lyophilized from a 0.22 μm filtered solution of PBS, pH7.4.Contact us for customized product form or formulation. |
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Species | Human |
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Calculated MW | 81.9 kDa |
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Background
This protein is a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene.
Product information
Synonym | DLG4; PSD95; SAP-90; SAP90; SAP-90; SAP90 |
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Expression Host | E. coli |
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Tag | N-His |
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Swiss-Prot | |
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Gene ID | |
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Usage guide
Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
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Reconstitution | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.