제품 > 항체 > 다중클론항체(pAb)

PSD95 Rabbit pAb (A7889)

Tested applications:WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP InhibitionReactivity:Human, Mouse, Rat

Western blot analysis of various lysates, using PSD95 Rabbit pAb (A7889) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 60s.

Overview

Product name	PSD95 Rabbit pAb
Catalog No.	A7889
Host species	Rabbit
Purification method	Affinity purification
Isotype	IgG

Background

This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen information

Immunogen	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PSD95 (NP_001308004.1).
Sequence	MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKII
Gene ID
Swiss Prot
Synonyms	MRD62; PSD95; SAP90; SAP-90
Calculated MW	80kDa
Observed MW	95kDa

Applications

Reactivity	Human, Mouse, Rat
Tested applications	WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP Inhibition
Recommended dilution	WB 1:500 - 1:1000
Storage buffer	Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Key application	Western blotting
Positive samples	Mouse brain, Rat brain
Cellular location	Cell junction, Cell membrane, Cell projection, Peripheral membrane protein, axon, postsynaptic cell membrane, postsynaptic density, synapse
Customer validation	WB(Mus musculus, Rattus norvegicus, Homo sapiens) IHC(Mus musculus)

Documents

Certificate of Compliance

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Research Area

PSD95 Rabbit pAb images

Western blot - PSD95 Rabbit pAb (A7889)

* For research use only. Not for therapeutic or diagnostic purposes.

Product Protocols

References for PSD95 Rabbit pAb (A7889)

Product:

PSD95 Rabbit pAb

Journal:

Cellular and molecular neurobiology

Application:

IF:

5.046

Species:

Mus musculus

PMID:

31401743

Title:

Experimental Autoimmune Prostatitis Induces Learning-Memory Impairment and Structural Neuroplastic Changes in Mice.

References for PSD95 Rabbit pAb (A7889)

Product:

PSD95 Rabbit pAb

Journal:

Psychopharmacology

Application:

IF:

4.53

Species:

Mus musculus

PMID:

31953648

Title:

Vortioxetine administration attenuates cognitive and synaptic deficits in 5×FAD mice

References for PSD95 Rabbit pAb (A7889)

Product:

PSD95 Rabbit pAb

Journal:

FASEB J

Application:

IF:

5.191

Species:

Mus musculus

PMID:

32812265

Title:

Morinda officinalis oligosaccharides ameliorate depressive‐like behaviors in poststroke rats through upregulating GLUT3 to improve synaptic activity

References for PSD95 Rabbit pAb (A7889)

Product:

PSD95 Rabbit pAb

Journal:

Biomed Pharmacother

Application:

IHC

IF:

6.529

Species:

Mus musculus

PMID:

33485120

Title:

The new coumarin compound Bis 3 ameliorates cognitive disorder and suppresses brain-intestine-liver systematic oxidative stress in high-fat diet mice

References for PSD95 Rabbit pAb (A7889)

Product:

PSD95 Rabbit pAb

Journal:

British journal of pharmacology

Application:

IF:

9.47

Species:

Mus musculus

PMID:

36727262

Title:

A glycine‐serine‐alanine‐rich peptide ameliorates Alzheimer‐type neurodegeneration

References for PSD95 Rabbit pAb (A7889)

Product:

PSD95 Rabbit pAb

Journal:

Cell death & disease

Application:

IF:

Species:

Rattus norvegicus, Homo sapiens

PMID:

37932279

Title:

ChemR23 activation attenuates cognitive impairment in chronic cerebral hypoperfusion by inhibiting NLRP3 inflammasome-induced neuronal pyroptosis - PMC

References for PSD95 Rabbit pAb (A7889)

Product:

PSD95 Rabbit pAb

Journal:

Frontiers in pharmacology

Application:

IF:

5.98

Species:

Rattus norvegicus

PMID:

37701028

Title:

Tirzepatide ameliorates spatial learning and memory impairment through modulation of aberrant insulin resistance and inflammation response in diabetic rats - PMC

References for PSD95 Rabbit pAb (A7889)

Product:

PSD95 Rabbit pAb

Journal:

International immunopharmacology

Application:

IF:

5.71

Species:

Mus musculus

PMID:

37001383

Title:

Lipin2 ameliorates diabetic encephalopathy via suppressing JNK/ERK-mediated NLRP3 inflammasome overactivation

References for PSD95 Rabbit pAb (A7889)

Product:

PSD95 Rabbit pAb

Journal:

Molecular neurobiology

Application:

IF:

5.68

Species:

Rattus norvegicus

PMID:

37380822

Title:

The Mitochondrial-Derived Peptide (MOTS-c) Interacted with Nrf2 to Defend the Antioxidant System to Protect Dopaminergic Neurons Against Rotenone Exposure

References for PSD95 Rabbit pAb (A7889)

Product:

PSD95 Rabbit pAb

Journal:

Molecular neurobiology

Application:

IF:

5.68

Species:

Rattus norvegicus

PMID:

37910285

Title:

Schisandrin A Alleviates Spatial Learning and Memory Impairment in Diabetic Rats by Inhibiting Inflammatory Response and Through Modulation of the PI3K/AKT

References for PSD95 Rabbit pAb (A7889)

Product:

PSD95 Rabbit pAb

Journal:

Behavioural brain research

Application:

IF:

2.7

Species:

Rattus norvegicus

PMID:

38825021

Title:

Effects of -asarone on spatial learning and memory impairment by exhaustive exercise-induced fatigue: Role of NR-CaMKII-ERK/CREB signal in hippocampus of rats

References for PSD95 Rabbit pAb (A7889)

Product:

PSD95 Rabbit pAb

Journal:

Antioxidants (Basel, Switzerland)

Application:

IF:

Species:

Mus musculus

PMID:

38929067

Title: