Overview
| Product name | Recombinant Human SR-B3/CD36 Protein |
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| Catalog No. | RP02182 |
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| Description | Recombinant Human SR-B3/CD36 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly30-Asn439) of human CD36 (Accession #P16671) fused with an hFc tag at the N-terminus. |
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| Purity | > 90% by SDS-PAGE. |
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| Endotoxin | < 0.1 EU/μg |
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| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
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| Species | Human |
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| Calculated MW | 72.58 kDa |
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Background
Platelet Glycoprotein 4 (CD36) is an integral membrane glycoprotein that has multiple physiological functions. It is broadly expressed on a variety of cell types including microvascular endothelium, adipocytes, skeletal muscle, epithelial cells of the retina, breast, and intestine, smooth muscle cells, erythroid precursors, platelets, megakaryocytes, dendritic cells, monocytes/macrophages, and microglia. As a member of the scavenger receptor family, CD36 is a multiligand pattern recognition receptor that interacts with a large number of structurally dissimilar ligands, including long chain fatty acid (LCFA), advanced glycation end products (AGE), thrombospondin-1, oxidized lowdensity lipoproteins (oxLDLs), high density lipoprotein (HDL), phosphatidylserine, apoptotic cells, β amyloid fibrils (fAβ), collagens I and IV, and Plasmodium falciparuminfected erythrocytes. CD36 is required for the antiangiogenic effects of thrombospondin-1 in the corneal neovascularization assay. It plays a role in lipid metabolism and has been identified as a fatty acid translocase necessary for the binding and transport of LCFA in cells and tissues.
Product information
| Synonym | BDPLT10; CHDS7; FAT; GP3B; GP4; GPIV; PASIV; SCARB3; CD36; BDPLT10; CHDS7; FAT; GP3B; GP4; GPIV; PASIV; SCARB3; CD36 molecule |
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| Expression Host | HEK293 cells |
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| Tag | N-hFc |
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| Swiss-Prot | |
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| Gene ID | |
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Usage guide
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
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| Reconstitution | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.
