| Product name | Rabbit anti-Human CCL2/MCP-1 mAb |
|---|---|
| Catalog No. | RM17902 |
| Catagory | Elisa Antibody Kit |
| Application | ELISA |
| Description | This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection. |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 22-99 of human CCL2/MCP-1 (NP_002973.1). |
| Purirty | Affinity purification |
| Ig Type | Rabbit IgG |
| Formulation | Supplied as a 0.2um filtered solution in PBS with 0.05%ProClin 300, PH 7.4. |
| CrossReactivity | No cross-reactivity in ELISA assay withrecombinant Human IL-3 , Human IL-4, Human IL-5, Human IL-6, Human IL-8, Human IL-10, Human IL-12, Human IFN-a |
| Storage | Store at -20℃. Avoid repeated freeze-thaw cycles. |
Human CCL2/MCP-1 Sandwich Immunoassay
| Recommended Concentration | Sample | ||
|---|---|---|---|
| ELISA | Capture | 0.5-2ug/mL | Rabbit anti-Human CCL2/MCP-1 mAb(Cat. No.RM17902) |
| Detection | 0.0025-0.01ug/mL | Rabbit anti-Human CCL2/MCP-1 mAb(Cat. No.RM17903) | |
| Standard | 31.25-2000pg/mL | Recombinant Human CCL2/MCP-1 Protein |
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