Rabbit anti-Human CD274 mAb (CAP) (RM17855)

Product name	Rabbit anti-Human CD274 mAb (CAP)
Catalog No.	RM17855
Catagory	Elisa Antibody Kit
Application	ELISA
Description	This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants.
Immunogen	Recombinant Human CD274
Purirty	Affinity purification
Ig Type	Rabbit IgG
Formulation	Supplied as a 0.2um filtered solution in PBS with 0.05%ProClin 300, PH 7.4.
CrossReactivity	/
Storage	Store at -20℃. Avoid freeze / thaw cycles. Preservative：0.05%ProClin 300. Avoid repeated freeze-thaw cycles.

Human CD274 Sandwich ELISA Immunoassay

	Recommended Concentration	Sample
ELISA Capture	1-4ug/mL	Rabbit anti-Human CD274(CAP)(Cat. No.RM17855)
ELISA Detection	0.05-0.2ug/mL	Rabbit anti-Human CD274(DET)(Cat. No.RM17856)
Standard	25-1600pg/mL	Recombinant Human CD274 Protein