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Rabbit anti-Human CD274 mAb (RMK0231)

Datasheet

ABclonal: - Rabbit anti-Human CD274 mAb (RMK0231)

Overview

Product nameRabbit anti-Human CD274 mAb
Catalog No.RMK0231
CatagoryElisa Antibody Kit
Applicationmultiplex assay
DescriptionThis gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants.
ImmunogenRecombinant Human CD274 Protein
PurirtyAffinity purification
Ig TypeRabbit IgG
FormulationSupplied as a 0.2um filtered solution in PBS, PH 7.4 containing Human CD274 Antibody.
CrossReactivity/
StorageStore at -20℃. Avoid freeze / thaw cycles. Preservative:0.05%ProClin 300.

Avoid repeated freeze-thaw cycles.

Application

Human CD274 multiplex assay

 Recommended
Concentration
Sample
Multiplex Capture3-20ug/mLRabbit anti-Human CD274 mAb(Cat. No.RMK0231)
Multiplex Detection0.017-2ug/mLRabbit anti-Human CD274 mAb(Cat. No.RMK0232)
Standard6.86-5000pg/mLRecombinant Human CD274 Protein
ABclonal: - Rabbit anti-Human CD274 mAb (RMK0231)}

- Rabbit anti-Human CD274 mAb (RMK0231)

This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

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