Overview
Product name | Biotinylated Recombinant Human PD-1/PDCD1/CD279 Protein |
---|
Catalog No. | RP00398B |
---|
Description | Biotinylated Recombinant Human PD-1/PDCD1/CD279 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu25-Gln167) of Human PD-1/PDCD1 (Accession #Q15116-1) fused with a C-His&Avi tag at the C-terminus. |
---|
Purity | > 95% by SDS-PAGE;> 95% by HPLC |
---|
Endotoxin | < 1 EU/μg of the protein by LAL method |
---|
Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
---|
Species | Human |
---|
Calculated MW | 18.9 kDa |
---|
Background
Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self tolerance by suppressing T cell inflammatory activity.
Product information
Synonym | PDCD1; PD1; CD279; SLEB2; PD-1 |
---|
Expression Host | HEK293 cells |
---|
Tag | C-His&Avi |
---|
Swiss-Prot | |
---|
Gene ID | |
---|
Usage guide
Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
---|
Reconstitution | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
---|
* For research use only. Not for therapeutic or diagnostic purposes.