Overview
Product name | Recombinant Human PRDX4 Protein |
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Catalog No. | RP03163LQ |
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Description | Recombinant Human PRDX4 Protein is produced by E.coli expression system. The target protein is expressed with sequence (Trp38-Asn271) of human PRDX4 (Accession #Q13162) fused with His tag at the N-terminus. |
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Purity | > 95% by SDS-PAGE. |
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Endotoxin | < 1.0 EU/μg of the protein by LAL method. |
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Formulation | Supplied as a 0.22 μm filtered solution in PBS, pH 7.4. Contact us for customized product form or formulation. |
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Species | Human |
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Calculated MW | 28.9 KDa |
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Background
Peroxiredoxin-4 (PRDX4) is a member of the AhpC/TSA family. PRDX4 is a cytoplasmic protein and contains one thioredoxin domain. PRDX4 exists in homodimer or heterodimer with PRDX1. PRDX4 reduces hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. In addition, PRDX4 is probably involved in redox regulation of the cell, regulating the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.
Product information
Synonym | Peroxiredoxin-4; Antioxidant Enzyme AOE372; AOE37-2; Peroxiredoxin IV; Prx-IV; Thioredoxin Peroxidase AO372; Thioredoxin-Dependent Peroxide Reductase A0372; PRDX4 |
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Expression Host | E.coli |
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Tag | N-His |
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Swiss-Prot | |
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Gene ID | |
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Usage guide
Storage | Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.