Recombinant Human TNFRSF10A/DR4/TRAIL-R1/CD261 Protein (RP02082)

Overview

Product name	Recombinant Human TNFRSF10A/DR4/TRAIL-R1/CD261 Protein
Catalog No.	RP02082
Description	Recombinant Human TNFRSF10A/DR4/TRAIL-R1/CD261 Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Ala109-Asn239) of Human TRAIL R1 / DR4 / TNFRSF10A fused with His tag at the C-terminal.
Purity	> 95% by Tris-Bis PAGE;> 95% by SEC-HPLC
Endotoxin	< 0.01 EU/μg
Formulation	Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
Species	Human
Calculated MW	15.14 kDa

Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A) is also known as TNF-related apoptosis-inducing ligand receptor 1 (TRAIL-R1), Death receptor 4 (DR4), CD261 and APO2, which belongs to TNF superfamily.The expression of apoptosis-inducing TRAIL-R1 and TRAIL-R2 and of the decoy receptors TRAIL-R3 and TRAIL-R4 was systematically studied in all developmental stages of peripheral B cells isolated from the blood and secondary lymphoid organs. Expression of TRAIL-Rs is modulated along development, with highest levels observed in germinal center B cells.

Product information

Synonym	TNFRSF10A; APO2; CD261; DR4; TRAILR-1; TRAILR1
Expression Host	HEK293 cells
Tag	C-His
Swiss-Prot
Gene ID

Usage guide

Storage	Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution	Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

* For research use only. Not for therapeutic or diagnostic purposes.