Recombinant Mouse SLAMF2/CD48 Protein (RP01591)

Overview

Product name	Recombinant Mouse SLAMF2/CD48 Protein
Catalog No.	RP01591
Description	Recombinant Mouse SLAMF2/CD48 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Phe23-Arg216) of mouse SLAMF2/CD48 (Accession #NP_031675.1) fused with a hFc tag at the C-terminus.
Bio-Activity	Measured by its binding ability in a functional ELISA. Immobilized Human CD48 (Catalog: RP01591) at 10 μg/mL (100 μL/well) can bind Human CD224 (Catalog: RP00167) with a linear range of 0.87-18.4 ng/mL.
Purity	> 95% by SDS-PAGE.
Endotoxin	<0.1EU/μg
Formulation	Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
Species	Mouse
Calculated MW	48.25 kDa

This protein is a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.

Product information

Synonym	BCM1; BLAST; BLAST1; hCD48; mCD48; MEM-102; SLAMF2; CD48
Expression Host	HEK293 cells
Tag	C-hFc
Swiss-Prot
Gene ID

Usage guide

Storage	Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution	Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

* For research use only. Not for therapeutic or diagnostic purposes.