Overview
Product name | Biotinylated Recombinant Human FGFR-2 beta (IIIb)/KGFR/CD332 Protein |
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Catalog No. | RP02535B |
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Description | Biotinylated Recombinant Human FGFR-2 beta (IIIb)/KGFR/CD332 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Arg152-Glu378) of human FGFR-2 beta (IIIb)/KGFR/CD332 (Accession #P21802-3) fused with His&Avi tag at the C-terminus. |
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Purity | > 95% by Tris-Bis PAGE and HPLC |
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Endotoxin | < 1 EU/μg of the protein by LAL method. |
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Formulation | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization. Contact us for customized product form or formulation. |
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Species | Human |
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Calculated MW | 28.3 kDa |
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Background
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs. A frequent splicing event involving FGF R1 and 2 results in receptors containing all three Ig domains, referred to as the alpha? isoform, or only IgII and IgIII, referred to as the beta? isoform.
Product information
Synonym | Fibroblast growth factor receptor 2;FGFR-2;KGFR;K-sam;Keratinocyte growth factor receptor;CD332;BEK;KSAM |
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Expression Host | HEK293 cells |
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Tag | C-His&Avi |
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Swiss-Prot | |
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Gene ID | |
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Usage guide
Storage | Store at -20℃. Store the lyophilized protein at -20℃ to -80℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
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Reconstitution | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.