제품 > 항체 > 다중클론항체(pAb)

FGFR2 Rabbit pAb (A2074)

Publication (1) Datasheet

Tested applications:WBIHC-PIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIPCUT&TagmeRIPInhibitionReactivity:Human, Mouse, Rat

ABclonal:Immunohistochemistry - FGFR2 Rabbit pAb (A2074)

Immunohistochemistry analysis of paraffin-embedded rat spleen using FGFR2 antibody (A2074) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

ABclonal:Immunohistochemistry - FGFR2 Rabbit pAb (A2074)

Immunohistochemistry analysis of paraffin-embedded human placenta using FGFR2 antibody (A2074) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

ABclonal:Immunohistochemistry - FGFR2 Rabbit pAb (A2074)

Immunohistochemistry analysis of paraffin-embedded mouse heart using FGFR2 antibody (A2074) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

Overview

Product nameFGFR2 Rabbit pAb
Catalog No.A2074
Host speciesRabbit
Purification methodAffinity purification
IsotypeIgG
The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 1-100 of human FGFR2 (NP_000132.3).
SequenceMVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPR
Gene ID
Swiss Prot
SynonymsBEK; JWS; BBDS; CEK3; CFD1; ECT1; KGFR; TK14; TK25; BFR-1; CD332; K-SAM
Calculated MW92kDa
Observed MWRefer to figures
ReactivityHuman, Mouse, Rat
Tested applicationsWBIHC-PIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIPCUT&TagmeRIPInhibition
Recommended dilution
  • IHC-P 1:50 - 1:200
Storage bufferStore at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Key applicationImmunohistochemistry    
Positive samples293T, LO2
Cellular locationCell membrane, Cytoplasmic vesicle, Golgi apparatus, Secreted, Single-pass type I membrane protein
Customer validation

WB(Homo sapiens)

IHC(Homo sapiens)

Documents

Certificate of Compliance

To download a Certificate of Compliance, please enter your Lot number below:

Lot number

ABclonal:Immunohistochemistry - FGFR2 Rabbit pAb (A2074)}

Immunohistochemistry - FGFR2 Rabbit pAb (A2074)

Immunohistochemistry analysis of paraffin-embedded rat spleen using FGFR2 antibody (A2074) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
ABclonal:Immunohistochemistry - FGFR2 Rabbit pAb (A2074)}

Immunohistochemistry - FGFR2 Rabbit pAb (A2074)

Immunohistochemistry analysis of paraffin-embedded human placenta using FGFR2 antibody (A2074) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
ABclonal:Immunohistochemistry - FGFR2 Rabbit pAb (A2074)}

Immunohistochemistry - FGFR2 Rabbit pAb (A2074)

Immunohistochemistry analysis of paraffin-embedded mouse heart using FGFR2 antibody (A2074) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

* For research use only. Not for therapeutic or diagnostic purposes.

Publishing research using A2074? Please let us know so that we can cite the reference in this datasheet.

항체 (3)

재조합 단백질 (8)

Secondary Antibodies (26)