Recombinant Human FGFR-2 beta (IIIb)/KGFR/CD332 (253-378) Protein (RP02529)

Overview

Product name	Recombinant Human FGFR-2 beta (IIIb)/KGFR/CD332 (253-378) Protein
Catalog No.	RP02529
Description	Recombinant Human FGFR-2 beta (IIIb)/KGFR/CD332 (253-378) Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Pro253-Glu378) of human FGFR-2 beta (IIIb)/KGFR/CD332 (Accession #P21802-3) fused with hFc tag at the C-terminus.
Purity	> 95% as determined by Tris-Bis PAGE；> 95% as determined by HPLC
Endotoxin	Less than 1EU per μg by the LAL method.
Species	Human
Calculated MW	40.5 kDa

Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs. A frequent splicing event involving FGF R1 and 2 results in receptors containing all three Ig domains, referred to as the alpha isoform, or only IgII and IgIII, referred to as the beta isoform.

Product information

Synonym	Fibroblast growth factor receptor 2；FGFR-2；KGFR；K-sam；Keratinocyte growth factor receptor；CD332；BEK；KSAM
Expression Host	HEK293 cells
Tag	C-hFc
Swiss-Prot
Gene ID

Usage guide

Storage	Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution	Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

* For research use only. Not for therapeutic or diagnostic purposes.