Overview
| Product name | Biotinylated Recombinant Human MS4A1/CD20 Protein |
|---|
| Catalog No. | RP00584BLQ |
|---|
| Description | Biotinylated Recombinant Human MS4A1/CD20 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Ile141-Ser188) of Human MS4A1/CD20 (Accession #P11836-1) fused with a C-His&Avi tag at the C-terminus. |
|---|
| Purity | > 95% by SDS-PAGE |
|---|
| Endotoxin | < 1 EU/μg of the protein by LAL method |
|---|
| Formulation | Supplied as 0.22 μm filtered solution in 20 mM PB, 10% Glycerol (pH 7.0). |
|---|
| Species | Human |
|---|
| Calculated MW | 16.8 kDa |
|---|
Background
B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R , CD117) and progressively increasing in concentration until maturity.CD20 is the target of the monoclonal antibodies rituximab, ocrelizumab, obinutuzumab, ofatumumab, ibritumomab tiuxetan, tositumomab, and ublituximab, which are all active agents in the treatment of all B cell lymphomas, leukemias, and B cell-mediated autoimmune diseases.
Product information
| Synonym | MS4A1; CD20; MS4A-1; B1; Bp35; CD20 receptor; CD20S7; CVID5; LEU-16; Ly-44; MS4A2; S7 |
|---|
| Expression Host | E. coli |
|---|
| Tag | C-His&Avi |
|---|
| Swiss-Prot | |
|---|
| Gene ID | |
|---|
Usage guide
| Storage | Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles. |
|---|
* For research use only. Not for therapeutic or diagnostic purposes.
A1_FC_01.jpg?t=1717744805)
i_FC_01.jpg?t=1718275694)
