Recombinant Human Lactate Dehydrogenase A/LDHA Protein (RP02791LQ)

Overview

Product name	Recombinant Human Lactate Dehydrogenase A/LDHA Protein
Catalog No.	RP02791LQ
Description	Recombinant Human Lactate Dehydrogenase A/LDHA Protein is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Phe332) of human Lactate Dehydrogenase A/LDHA (Accession #NP_005557.1) fused with a 6×His tag at the N-terminus.
Purity	> 95% by SDS-PAGE.
Endotoxin	<1EU/μg
Formulation	Supplied as a 0.22 μm filtered solution in 20mM Tris, 250mM NaCl, 10% Glycerol, pH8.0.
Species	Human
Calculated MW	37.53 kDa

L-Lactate Dehydrogenase A Chain (LDHA) is an enzyme that catalyzes the conversion of L-lactate and NAD+ to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA contains an N-terminal coenzyme binding region, a central catalytic site, and at least nine utilized Lys acetylation and two Tyr phosphorylation sites. LDHA belongs to the lactate dehydrogenase family, expressed predominantly in muscle tissue. LDHA mutations have been linked to exertional myoglobinuria.

Product information

Synonym	LDHM; GSD11; PIG19; HEL-S-133P; LDHA
Expression Host	E. coli
Tag	N-His
Swiss-Prot
Gene ID

Usage guide

Storage	Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles.

* For research use only. Not for therapeutic or diagnostic purposes.