PE-Labeled Recombinant Human HER1/ERBB1/EGFR (25-378) Protein (RP00500PLQ)

Overview

Product name	PE-Labeled Recombinant Human HER1/ERBB1/EGFR (25-378) Protein
Catalog No.	RP00500PLQ
Description	PE-Labeled Recombinant Human ERBB1/HER1/EGFR (25-378) Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu25-Ser378) of Human ERBB1/HER1/EGFR (25-378) (Accession #NP_001333870.1) fused with a C-His&Avi tag at the C-terminus.
Endotoxin	< 1 EU/μg of the protein by LAL method
Formulation	Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Species	Human
Calculated MW	41.6 kDa

The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with EGFR gene amplification frequently contain EGFR gene rearrangements, with the most common extracellular domain mutation being EGFRvIII. This mutation leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand.

Product information

Synonym	ErbB; EC 2.7.10; EC 2.7.10.1; EGFR; mENA; LEGFR; ERBB; ERBB1; HER1; PIG61; NISBD2
Expression Host	HEK293 cells
Tag	C-His&Avi
Swiss-Prot
Gene ID

Usage guide

Storage	Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles.

* For research use only. Not for therapeutic or diagnostic purposes.