Overview
Product name | Recombinant Human Bcl-2 Protein |
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Catalog No. | RP00062LQ |
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Description | Recombinant Human Bcl-2 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Ala2-Asp211) of human BCL2 (Accession #NP_000624.2). |
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Bio-Activity | Measured by its binding ability in a functional ELISA. Immobilized Human BCL-XL Protein at 2 μg/mL (100 μL/well) can bind BCL2 with a linear range of 3.9-421 ng/mL.
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Purity | > 95% by SDS-PAGE. |
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Endotoxin | Please contact us for more information. |
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Formulation | Supplied in 20mM Tris,200mM NaCl,30% Glycerol,1mM DTT, pH 8.0Contact us for customized product form or formulation. |
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Species | Human |
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Calculated MW | 23.17 kDa |
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Background
This protein is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma.
Product information
Synonym | BCL2; Bcl-2; PPP1R50; apoptosis regulator Bcl-2; Bcl-2; PPP1R50 |
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Expression Host | E. coli |
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Tag | No tag |
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Swiss-Prot | |
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Gene ID | |
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Usage guide
Storage | Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.