Overview
| Product name | Recombinant Human Beta-actin/ACTB Protein |
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| Catalog No. | RP02968LQ |
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| Description | Recombinant Human Beta-actin/ACTB Protein is produced by E. coli expression system. The target protein is expressed with sequence (Asp2-Phe375) of Human Beta-actin/ACTB (Accession #NP_001092.1) fused with a 6×His tag at the C-terminus. |
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| Purity | > 90% by SDS-PAGE. |
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| Endotoxin | <1EU/μg |
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| Formulation | Supplied as a 0.2 μm filtered solution of 10mM Tris-HCl, 0.1% TritonX-100, 2mM DTT, 10% Glycerol, pH 8.0. |
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| Species | Human |
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| Calculated MW | 42.8 kDa |
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Background
Actins are ubiquitous globular and highly conserved proteins that are involved in various types of cell motility, structure, and integrity. Three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. ACTB is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others.
Product information
| Synonym | Actin Cytoplasmic 1; Beta-Actin; ACTB; β-actin |
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| Expression Host | E. coli |
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| Tag | C-His |
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| Swiss-Prot | |
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| Gene ID | |
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Usage guide
| Storage | Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.
