Rabbit anti-Human TNF-alpha mAb (RM17658)

Product name	Rabbit anti-Human TNF-alpha mAb
Catalog No.	RM17658
Catagory	Elisa Antibody Kit
Application	ELISA, Multiplex, CLIA
Description	This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, psoriasis, rheumatoid arthritis ankylosing spondylitis, tuberculosis, autosomal dominant polycystic kidney disease, and cancer. Mutations in this gene affect susceptibility to cerebral malaria, septic shock, and Alzheimer disease. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Immunogen	Recombinant TNF-alpha Protein
Purirty	Affinity purification
Ig Type	Rabbit IgG
Endotoxin Level	< 1.0 EU/μg of the protein by LAL method.
Formulation	upplied as a 0.2μm filtered solution in PBS with 0.05% Proclin300, PH 7.4.
CrossReactivity	No cross-reactivity in ELISA assay with recombinant hNFKB1 、mTNFA、rTNFA
Storage	Store at -20℃. Avoid repeated freeze-thaw cycles.

Human TNF-alpha Sanwich ELISA/Sanwich CLIA

		Recommended Concentration	Sample
ELISA	Capture	0.5-2ug/mL	Rabbit anti-Human TNF-alpha(Cat. No.RM17657)
	Detection	0.006-0.025ug/mL	Rabbit anti-Human TNF-alpha(Cat. No.RM17658)
	Standard	7.81-500pg/mL	Recombinant Human TNF-alpha Protein
CLIA	Capture	1-4ug/mL	Rabbit anti-Human TNF-alpha(Cat. No.RM17748)
	Detection	0.5-2ug/mL	Rabbit anti-Human TNF-alpha(Cat. No.RM17658)
	Standard	10-1000pg/mL	Recombinant Human TNF-alpha Protein