| Product name | Rabbit anti-Human TNF-alpha mAb |
|---|---|
| Catalog No. | RM17657 |
| Catagory | Elisa Antibody Kit |
| Application | ELISA, Multiplex |
| Description | This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, psoriasis, rheumatoid arthritis ankylosing spondylitis, tuberculosis, autosomal dominant polycystic kidney disease, and cancer. Mutations in this gene affect susceptibility to cerebral malaria, septic shock, and Alzheimer disease. Knockout studies in mice also suggested the neuroprotective function of this cytokine. |
| Immunogen | Recombinant TNF-alpha Protein |
| Purirty | Affinity purification |
| Ig Type | Rabbit IgG |
| Formulation | Supplied as a 0.2μm filtered solution in PBS with 0.05% Proclin300, PH 7.4. |
| CrossReactivity | No cross-reactivity in ELISA assay with recombinant hNFKB1 、mTNFA、rTNFA |
| Storage | Store at -20℃. Avoid repeated freeze-thaw cycles. |
Human TNF-alpha Sanwich ELISA
| Recommended Concentration | Sample | ||
|---|---|---|---|
| ELISA | Capture | 0.5-2ug/mL | Rabbit anti-Human TNF-alpha(Cat. No.RM17657) |
| Detection | 0.006-0.025ug/mL | Rabbit anti-Human TNF-alpha(Cat. No.RM17658) | |
| Standard | 7.81-500pg/mL | Recombinant Human TNF-alpha Protein |
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