| Product name | Rabbit anti-Human TNF-alpha(CAP) |
|---|---|
| Catalog No. | RM17698 |
| Catagory | Elisa Antibody Kit |
| Application | multiplex assay |
| Description | This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, psoriasis, rheumatoid arthritis ankylosing spondylitis, tuberculosis, autosomal dominant polycystic kidney disease, and cancer. Mutations in this gene affect susceptibility to cerebral malaria, septic shock, and Alzheimer disease. Knockout studies in mice also suggested the neuroprotective function of this cytokine. |
| Immunogen | E. coli-derived human TNF-alpha protein Val77-Leu233 Accession #P01375 |
| Purirty | Affinity purification |
| Ig Type | Rabbit IgG |
| Formulation | Supplied as a 0.2um filtered solution in PBS with 0.1%Braveds MB-1, PH 7.4. |
| CrossReactivity | No cross-reactivity in multiplex assay with recombinant hCD40 Ligand, TNF-β, rTNF-α, mTNF-α |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. Preservative：0.05%ProClin 300. Avoid repeated freeze-thaw cycles. |
i_FC_01.jpg?t=1704936030)
Y_FC_01.jpg?t=1704936255)
