Rabbit anti-Human TNF-alpha mAb (RM17748)

Product name	Rabbit anti-Human TNF-alpha mAb
Catalog No.	RM17748
Catagory	Elisa Antibody Kit
Application	CLIA
Description	This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, psoriasis, rheumatoid arthritis ankylosing spondylitis, tuberculosis, autosomal dominant polycystic kidney disease, and cancer. Mutations in this gene affect susceptibility to cerebral malaria, septic shock, and Alzheimer disease. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Immunogen	Recombinant Human TNF-alpha Protein
Purirty	Affinity purification
Ig Type	Rabbit IgG
Formulation	Supplied as a 0.2μm filtered solution in PBS with 0.05% Proclin300, PH 7.4.
CrossReactivity	No cross-reactivity in ELISA with recombinant hNFKB1 、mTNFA、rTNFA
Storage	Store at -20℃. Avoid repeated freeze-thaw cycles.

Human TNF-alpha Sandwich Immunoassay

		Recommended Concentration	Sample
CLIA	Capture	1-4ug/mL	Rabbit anti-Human TNF-alpha mAb(Cat. No.RM17748)
	Detection	0.5-2ug/mL	Rabbit anti-Human TNF-alpha mAb(Cat. No.RM17658)
	Standard	10-1000pg/mL	Recombinant Human TNF-alpha Protein