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Human VEGF Monoclonal Antibody (YR0008)

Direct ELISA binding curve demonstrating the recognition of Human Anti-Human VEGF (Research Grade Bevacizumab Biosimilar) Monoclonal Antibody to VEGF. The target protein was coated onto the microplate well surface, followed by binding of the antibody. A donkey anti-human IgG HRP conjugate was used for detection.

Through SPR measurement, the human anti-human VEGF-A (Research Grade Bevacizumab Biosimila) monoclonal antibody is capable of binding to human VEGF-A with an affinity greater than 1pM.

Basic Information

Clone	Bevacizumab Biosimilar
Molecular Weight	150 kDa
Endotoxin	<1EU/mg (<0.001EU/μg)Determined by LAL gel clotting assay
Sterility	0.2 μm filtration
Aggregation	<5% Determined by SECP
Purity	>95% Determined by SEC-HPLC

Product Information

Production	Purified from cell culture supernatant in an animal-free facility
Purification	Protein A or G purification
Storage	2 - 8°C for up to 4 weeks and -80°C for long term storage (Avoid repeated freezing and thawing)

Target Background

Bevacizumab, the humanized anti-VEGF-A monoclonal antibody, produces angiogenesis inhibition and slows the growth of new blood vessels. As the first clinically available angiogenesis inhibitor in the United States, Bevacizumab is used for treatment of certain metastatic cancers, certain lung cancers, renal cancers, ovarian cancers, breast cancers, and glioblastoma multiforme of the brain.Vascular endothelial growth factor A (VEGF-A) stimulates angiogenesis in a variety of cancers, including colorectal, lung, breast, glioblastoma, kidney, and ovarian cancers.

Immunogen Information

Isotype	Human IgG1 kappa
Immunogen	Human VGEF
RecommendedIsotype Control(s)	In Vivo Grade Recombinant Human IgG1 Kappa Isotype Control Antibody
Recommended Dilution Buffer	1×PBS pH 7.0

Human VEGF Monoclonal Antibody images

- Human VEGF Monoclonal Antibody (YR0008)

Through SPR measurement, the human anti-human VEGF-A (Research Grade Bevacizumab Biosimila) monoclonal antibody is capable of binding to human VEGF-A with an affinity greater than 1pM.

* For research use only. Not for therapeutic or diagnostic purposes.