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2'-O-Methylguanosine(Gm) Rabbit mAb (A20696)

Datasheet

Tested applications:WBIHC-PIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIPCUT&TagmeRIPInhibitionReactivity:Species independent

ABclonal:Dot Blot - 2'-O-Methylguanosine(Gm) Rabbit mAb (A20696)

The 2'-O-methylguanosine(Gm) Rabbit mAb (A20696) are tested in Dot Blot against 2'-O-methylguanosine and unmodified guanosine.2'-O-methylguanosine:Biotin-5'GCATAATGACTACT(Gm)3'unmodified guanosine:Biotin-5'GCATAATGACTACTG3'

Overview

Product name2'-O-Methylguanosine(Gm) Rabbit mAb
Catalog No.A20696
Host speciesRabbit
Purification methodAffinity purification
IsotypeIgG
CloneNo.ARC50772
RNA methylation plays a significant regulatory role in various of physiological activities and it has gradually become a hotspot of epigenetics in the past decade. 2'-O-methyladenosine (Am), 2'-O-methylguanosine (Gm), 2'-O-methylcytidine (Cm), 2'-O-methyluridine (Um), N 6-methyladenosine (m6A), N 1-methylguanosine (m1G), 5-methylcytidine (m5C), and 5-methyluridine (m5U) are representative 2'-O-methylation and base-methylation modified epigenetic marks of RNA. 2'-O-methyltransferase is a modified nucleoside that is produced in tRNAs by the action of tRNA guanosine-2'-O-methyltransferase, using S-adenosyl-L-methionine as a substrate. Through its interaction with other modified nucleosides, 2'-O-methylguanosine is thought to stabilize the structure of the tRNA.
ImmunogenGm
SequenceGm conjugated to KLH
Gene ID
Swiss Prot
Synonyms2'-O-Methylguanosine; Gm
Calculated MW
Observed MWRefer to figures
ReactivitySpecies independent
Tested applicationsWBIHC-PIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIPCUT&TagmeRIPInhibition
Recommended dilution
  • DB 1:500 - 1:2000
Storage bufferStore at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Key application
Positive samples
Cellular location

Documents

Certificate of Compliance

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Lot number

    ABclonal:Dot Blot - 2'-O-Methylguanosine(Gm) Rabbit mAb (A20696)}

    Dot Blot - 2'-O-Methylguanosine(Gm) Rabbit mAb (A20696)

    The 2'-O-methylguanosine(Gm) Rabbit mAb (A20696) are tested in Dot Blot against 2'-O-methylguanosine and unmodified guanosine.2'-O-methylguanosine:Biotin-5'GCATAATGACTACT(Gm)3'unmodified guanosine:Biotin-5'GCATAATGACTACTG3'

    * For research use only. Not for therapeutic or diagnostic purposes.

    Secondary Antibodies (26)