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2'-O-methyluridine(Um) Rabbit mAb (A20695)

Tested applications:WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP InhibitionReactivity:Species independent

Dot-blot analysis of 2'-O-methyluridine(Um) and unmodified uridine using 2'-O-methyluridine(Um) Rabbit mAb antibody (A20695) at 1:1000 dilution.
2'-O-methyluridine : Biotin-5'UGACAACUACAGAC(Um)3'
unmodified uridine : Biotin-5'UGACAACUACAGACU3'

Overview

Product name	2'-O-methyluridine(Um) Rabbit mAb
Catalog No.	A20695
Host species	Rabbit
Purification method	Affinity purification
Isotype	IgG
CloneNo.	ARC50750

Background

Ribose methylation is among the most ubiquitous modifications found in RNA. 2'-O-methyluridine is found in rRNA, snRNA, snoRNA and tRNA of Archaea, Bacteria, and Eukaryota. Moreover, 2'-O-methylribonucleosides are promising starting materials for the production of nucleic acid-based drugs. The chemical modification 2'-O-methyl of nucleosides is often used to increase siRNA stability towards nuclease activities.

Immunogen information

Immunogen	Um
Sequence	Um conjugated to KLH
Gene ID
Swiss Prot
Synonyms	Um; 2'-O-methyluridine; 2'-O-methyluridine(Um)
Calculated MW
Observed MW	Refer to figures

Applications

Reactivity	Species independent
Tested applications	WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP Inhibition
Recommended dilution	DB 1:500 - 1:1000
Storage buffer	Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Key application
Positive samples	2'-O-methyluridine(Um)
Cellular location