제품 > 항체 > 단일클론항체(mAb)

ABflo® 647 Rabbit anti-Human CD201/EPCR mAb (A24227)

Tested applications:WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP InhibitionReactivity:Human

Flow cytometry: 1X10^6 Jurkat cells(low Expression, left) and A549 (right) were surface-stained with ABflo® 647 Rabbit anti-Human CD201/EPCR mAb(A24227, 5 μl/Test, orange line) or ABflo® 647 Rabbit IgG isotype control (A22070, 5 μl/Test, blue line).Non-fluorescently stained cells was used as blank control (red line).

Flow cytometry:1X10^6 A549 cells were surface-stained with ABflo® 647 Rabbit IgG isotype control (A22070, 5 μl/Test, left) or ABflo® 647 Rabbit anti-Human CD201/EPCR mAb(A24227, 5 μl/Test, right).

Overview

Product name	ABflo® 647 Rabbit anti-Human CD201/EPCR mAb
Catalog No.	A24227
Host species	Rabbit
Purification method	Affinity purification
Isotype	IgG
CloneNo.	ARC60942-ABflo647

Background

The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer.

Immunogen information

Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 18-210 of human CD201/EPCR (NP_006395.2).
Sequence	QDASDGLQRLHMLQISYFRDPYHVWYQGNASLGGHLTHVLEGPDTNTTIIQLQPLQEPESWARTQSGLQSYLLQFHGLVRLVHQERTLAFPLTIRCFLGCELPPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGVVTFTLQQLNAYNRTRYELREFLEDTCVQYVQKHISAENTKGSQTSRSYTS
Gene ID
Swiss Prot
Synonyms	PROCR; CCCA; CCD41; EPCR; protein C receptor
Calculated MW	26kDa
Observed MW

Applications

Reactivity	Human
Tested applications	WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP Inhibition
Recommended dilution	FC 5 μl per 10^6 cells in 100 μl volume
Storage buffer	Store at 2-8℃. Avoid freeze. Buffer: PBS with 0.03% proclin300, 0.2% BSA, pH7.3.
Key application	Flow Cytometry
Positive samples
Cellular location	Membrane, Single-pass type I membrane protein.
Customer validation	FC(Homo sapiens)