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IDO1 Rabbit mAb (A12125)

Publication (2) Datasheet

Tested applications:WBIHC-PIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIPCUT&TagmeRIPInhibitionReactivity:Human, Mouse

ABclonal:Immunohistochemistry - IDO1 Rabbit mAb (A12125)

Immunohistochemistry analysis of paraffin-embedded Human liver using IDO1 Rabbit mAb (A12125) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.

ABclonal:Immunohistochemistry - IDO1 Rabbit mAb (A12125)

Immunohistochemistry analysis of paraffin-embedded Mouse spinal cord using IDO1 Rabbit mAb (A12125) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.

Overview

Product nameIDO1 Rabbit mAb
Catalog No.A12125
Host speciesRabbit
Purification methodAffinity purification
IsotypeIgG
CloneNo.ARC0560
This gene encodes indoleamine 2, 3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 50-150 of human IDO1 (P14902).
SequenceIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDV
Gene ID
Swiss Prot
SynonymsIDO; INDO; IDO-1; IDO1
Calculated MW45kDa
Observed MW42kDa
ReactivityHuman, Mouse
Tested applicationsWBIHC-PIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIPCUT&TagmeRIPInhibition
Recommended dilution
  • IHC-P 1:50 - 1:200
Storage bufferStore at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Key applicationImmunohistochemistry    
Positive samplesMouse ovary
Cellular locationcytoplasm, cytosol.
Customer validation

WB(Homo sapiens,Mus musculus)

Documents

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ABclonal:Immunohistochemistry - IDO1 Rabbit mAb (A12125)}

Immunohistochemistry - IDO1 Rabbit mAb (A12125)

Immunohistochemistry analysis of paraffin-embedded Human liver using IDO1 Rabbit mAb (A12125) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
ABclonal:Immunohistochemistry - IDO1 Rabbit mAb (A12125)}

Immunohistochemistry - IDO1 Rabbit mAb (A12125)

Immunohistochemistry analysis of paraffin-embedded Mouse spinal cord using IDO1 Rabbit mAb (A12125) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.

* For research use only. Not for therapeutic or diagnostic purposes.

Publishing research using A12125? Please let us know so that we can cite the reference in this datasheet.

항체 (3)

재조합 단백질 (1)

Secondary Antibodies (26)