제품 > 항체 > 다중클론항체(pAb)

IKKβ Rabbit pAb (A2087)

Tested applications:WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP InhibitionReactivity:Human, Mouse, Rat

Immunofluorescence analysis of NIH/3T3 cells using IKKβ Rabbit pAb (A2087) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (AS007) at 1:500 dilution. Blue: DAPI for nuclear staining.

Review

Overview

Product name	IKKβ Rabbit pAb
Catalog No.	A2087
Host species	Rabbit
Purification method	Affinity purification
Isotype	IgG

Background

The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene.

Immunogen information

Immunogen	A synthetic peptide corresponding to a sequence within amino acids 400-669 of human IKKβ (NP_001547.1).
Sequence	QISPRPQPESVSCILQEPKRNLAFFQLRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMNLLRNNSCLSKMKNSMASMSQQLKAKLDFFKTSIQIDLEKYSEQTEFGITSDKLLLAWREMEQAVELCGRENEVKLLVERMMALQTDIVDLQRSPMGRKQGGTLDDLEEQARELYRRLREKPRDQRTEGDSQEMVRLLLQAIQSFEKKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMNEDEKTVVRLQEKRQKELWNLLKIACSKVRGPV
Gene ID
Swiss Prot
Synonyms	IKK2; IKKB; IMD15; IMD15A; IMD15B; NFKBIKB; IKK-beta
Calculated MW	87kDa
Observed MW	87kDa

Applications

Reactivity	Human, Mouse, Rat
Tested applications	WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP Inhibition
Recommended dilution	WB 1:500 - 1:1000 IHC-P 1:50 - 1:200 IF/ICC 1:50 - 1:200
Storage buffer	Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Key application	Western blotting Immunohistochemistry Immunofluorescence
Positive samples	Mouse spleen
Cellular location	Cytoplasm, Membrane raft, Nucleus
Customer validation	(Raw264.7) WB(Homo sapiens, Mus musculus, Rattus norvegicus, Mus musculus) IHC(Rattus norvegicus)

Documents

Certificate of Compliance

To download a Certificate of Compliance, please enter your Lot number below:

Lot number

Research Area

IKKβ Rabbit pAb images

Immunofluorescence - IKKβ Rabbit pAb (A2087)

* For research use only. Not for therapeutic or diagnostic purposes.

Submit an review for A2087

Please submit reviews to your technical sales specialist directly. Alternatively, email us at info@abclonal.co.kr

Reviews List

Product Protocols

References for IKKβ Rabbit pAb (A2087)

Product:

IKKβ Rabbit pAb

Journal:

Oncogenesis

Application:

IF:

7.485

Species:

Homo sapiens

PMID:

28945218

Title:

TNFα-YAP/p65-HK2 axis mediates breast cancer cell migration

References for IKKβ Rabbit pAb (A2087)

Product:

IKKβ Rabbit pAb

Journal:

International Journal of Molecular Medicine

Application:

IF:

4.101

Species:

Mus musculus

PMID:

29138800

Title:

Broadleaf Mahonia attenuates granulomatous lobular mastitis?associated inflammation by inhibiting CCL?5 expression in macrophages

References for IKKβ Rabbit pAb (A2087)

Product:

IKKβ Rabbit pAb

Journal:

International Immunopharmacology

Application:

IF:

4.932

Species:

Rattus norvegicus

PMID:

31874368

Title:

The key role of macrophage depolarization in the treatment of COPD with ergosterol both in vitro and in vivo

References for IKKβ Rabbit pAb (A2087)

Product:

IKKβ Rabbit pAb

Journal:

Journal of Cellular and Molecular Medicine

Application:

IF:

5.31

Species:

Homo sapiens

PMID:

31755231

Title:

Inhibition of DNM1L and mitochondrial fission attenuates inflammatory response in fibroblast-like synoviocytes of rheumatoid arthritis

References for IKKβ Rabbit pAb (A2087)

Product:

IKKβ Rabbit pAb

Journal:

Aging Dis

Application:

IF:

6.74

Species:

Mus musculus

PMID:

32489699

Title:

Mib2 Deficiency Inhibits Microglial Activation and Alleviates Ischemia-Induced Brain Injury

References for IKKβ Rabbit pAb (A2087)

Product:

IKKβ Rabbit pAb

Journal:

ACS Appl Mater Interfaces

Application:

IF:

9.229

Species:

Mus musculus,Rattus norvegicus

PMID:

34618442

Title:

Layered Double Hydroxide Nanoparticles with Osteogenic Effects as miRNA Carriers to Synergistically Promote Osteogenesis of MSCs

References for IKKβ Rabbit pAb (A2087)

Product:

IKKβ Rabbit pAb

Journal:

Exp Ther Med

Application:

IHC

IF:

2.447

Species:

Rattus norvegicus

PMID:

34603527

Title:

Gentianella acuta mitigates cardiovascular damage and inflammation in diet?induced hypercholesterolaemic rats

References for IKKβ Rabbit pAb (A2087)

Product:

IKKβ Rabbit pAb

Journal:

Evidence-based complementary and alternative medicine : eCAM

Application:

IF:

2.65

Species:

Rattus norvegicus

PMID:

36118087

Title:

KL-FGF23-VD Axis in Improving Late-Onset Alzheimer's Disease by Modulating IKK/NF-κB Signal Pathway - PMC

References for IKKβ Rabbit pAb (A2087)

Product:

IKKβ Rabbit pAb

Journal:

Cell Death & Disease

Application:

IF:

9.685

Species:

Homo sapiens, Mus musculus

PMID:

30158589

Title:

CXCL1 derived from tumor-associated macrophages promotes breast cancer metastasis via activating NF-B/SOX4 signaling.

References for IKKβ Rabbit pAb (A2087)

Product:

IKKβ Rabbit pAb

Journal:

Chinese herbal medicines

Application:

IF:

Species:

Rattus norvegicus

PMID:

36875432

Title:

Protective effect of hydroxysafflor yellow A on MSCs against senescence induced by D-galactose

References for IKKβ Rabbit pAb (A2087)

Product:

IKKβ Rabbit pAb

Journal:

Planta Med

Application:

IF:

3.007

Species:

Mus musculus

PMID:

34293804

Title:

Suffrutines A and B Inhibit the Expression of Inflammatory Mediators in LPS-Induced RAW264. 7 Cells by Suppressing the NF-B Signaling Pathway

References for IKKβ Rabbit pAb (A2087)

Product:

IKKβ Rabbit pAb

Journal:

Journal of translational medicine

Application:

IF:

7.4

Species:

Mus musculus

PMID:

38840216

Title:

S1PR3 inhibition protects against LPS-induced ARDS by inhibiting NF-B and improving mitochondrial oxidative phosphorylation - PMC

Publishing research using A2087? Please let us know so that we can cite the reference in this datasheet.

항체 (3)

Secondary Antibodies (26)

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제품 > 항체 > 다중클론항체(pAb)

IKKβ Rabbit pAb (A2087)

Overview

Background

Immunogen information

Applications

Documents

Certificate of Compliance

Research Area

IKKβ Rabbit pAb images

Submit an review for A2087

Reviews List

Product Protocols

항체 (3)

Secondary Antibodies (26)