SETD1A Rabbit pAb (A17314)

Datasheet

Tested applications:WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP InhibitionReactivity:Human, Rat

Overview

Product name	SETD1A Rabbit pAb
Catalog No.	A17314
Host species	Rabbit
Purification method	Affinity purification
Isotype	IgG

The protein encoded by this gene is a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at Lys4. Trimethylation of histone H3 at lysine 4 (H3K4me3) is a chromatin modification known to generally mark the transcription start sites of active genes. The protein contains SET domains, a RNA recognition motif domain and is a member of the class V-like SAM-binding methyltransferase superfamily.

Immunogen information

Immunogen	A synthetic peptide corresponding to a sequence within amino acids 300-400 of human SETD1A (NP_055527.1).
Sequence	RSENSYQDAFSRRHFSASSASTTASTAIAATTAATASSSASSSSLSSSSSSSSSSSSSQFRSSDANYPAYYESWNRYQRHTSYPPRRATREEPPGAPFAEN
Gene ID
Swiss Prot
Synonyms	Set1; EPEDD; KMT2F; Set1A; NEDSID
Calculated MW	186kDa
Observed MW	Refer to figures

Applications

Reactivity	Human, Rat
Tested applications	WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP Inhibition
Recommended dilution
Storage buffer	Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Key application
Positive samples
Cellular location	histone methyltransferase complex, nuclear speck, nucleoplasm, nucleus
Customer validation	WB(Mus musculus)