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ETV1 Rabbit pAb (A13303)

Datasheet

Tested applications:WBIHC-PIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIPCUT&TagmeRIPInhibitionReactivity:Human, Mouse, Rat

ABclonal:Immunohistochemistry - ETV1 Rabbit pAb (A13303)

Immunohistochemistry analysis of paraffin-embedded rat pancreas using ETV1 Rabbit pAb (A13303) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

ABclonal:Immunohistochemistry - ETV1 Rabbit pAb (A13303)

Immunohistochemistry analysis of paraffin-embedded human breast cancer using ETV1 Rabbit pAb (A13303) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

ABclonal:Immunohistochemistry - ETV1 Rabbit pAb (A13303)

Immunohistochemistry analysis of paraffin-embedded mouse pancreas using ETV1 Rabbit pAb (A13303) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

ABclonal:Immunofluorescence - ETV1 Rabbit pAb (A13303)

Immunofluorescence analysis of A549 cells using ETV1 Rabbit pAb (A13303).Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (AS007) at 1:500 dilution.

Overview

Product nameETV1 Rabbit pAb
Catalog No.A13303
Host speciesRabbit
Purification methodAffinity purification
IsotypeIgG
This gene encodes a member of the ETS (E twenty-six) family of transcription factors. The ETS proteins regulate many target genes that modulate biological processes like cell growth, angiogenesis, migration, proliferation and differentiation. All ETS proteins contain an ETS DNA-binding domain that binds to DNA sequences containing the consensus 5'-CGGA[AT]-3'. The protein encoded by this gene contains a conserved short acidic transactivation domain (TAD) in the N-terminal region, in addition to the ETS DNA-binding domain in the C-terminal region. This gene is involved in chromosomal translocations, which result in multiple fusion proteins including EWS-ETV1 in Ewing sarcoma and at least 10 ETV1 partners (see PMID: 19657377, Table 1) in prostate cancer. In addition to chromosomal rearrangement, this gene is overexpressed in prostate cancer, melanoma and gastrointestinal stromal tumor. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 80-300 of human ETV1 (NP_004947.2).
SequenceAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSYGEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSYPMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNTMVGSAASQSFPPPLMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPRQ
Gene ID
Swiss Prot
SynonymsER81; ETV1
Calculated MW55kDa
Observed MW
ReactivityHuman, Mouse, Rat
Tested applicationsWBIHC-PIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIPCUT&TagmeRIPInhibition
Recommended dilution
  • IHC-P 1:50 - 1:200
  • IF/ICC 1:50 - 1:200
Storage bufferStore at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Key applicationImmunohistochemistry    Immunofluorescence    
Positive samples
Cellular locationNucleus

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ABclonal:Immunohistochemistry - ETV1 Rabbit pAb (A13303)}

Immunohistochemistry - ETV1 Rabbit pAb (A13303)

Immunohistochemistry analysis of paraffin-embedded rat pancreas using ETV1 Rabbit pAb (A13303) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
ABclonal:Immunohistochemistry - ETV1 Rabbit pAb (A13303)}

Immunohistochemistry - ETV1 Rabbit pAb (A13303)

Immunohistochemistry analysis of paraffin-embedded human breast cancer using ETV1 Rabbit pAb (A13303) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
ABclonal:Immunohistochemistry - ETV1 Rabbit pAb (A13303)}

Immunohistochemistry - ETV1 Rabbit pAb (A13303)

Immunohistochemistry analysis of paraffin-embedded mouse pancreas using ETV1 Rabbit pAb (A13303) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
ABclonal:Immunofluorescence - ETV1 Rabbit pAb (A13303)}

Immunofluorescence - ETV1 Rabbit pAb (A13303)

Immunofluorescence analysis of A549 cells using ETV1 Rabbit pAb (A13303).Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (AS007) at 1:500 dilution.

* For research use only. Not for therapeutic or diagnostic purposes.

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