제품 > 항체 > 단일클론항체(mAb)

PE Rabbit anti-Human MRC2 mAb (A26561)

Tested applications:WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP InhibitionReactivity:Human

Flow cytometry: 1X10^6 Daudi cells (negative control, left) and U-138MG cells (right) were surface-stained with PE Rabbit anti-Human MRC2 mAb (A26561, 5 μl/Test, orange line) or PE Rabbit IgG isotype control (A24172, 5 μl/Test, blue line). Non-fluorescently stained cells were used as blank control (red line).

Flow cytometry: 1X10^6 U-138MG cells were surface-stained with PE Rabbit IgG isotype control (A24172, 5 μl/Test, left) or PE Rabbit anti-Human MRC2 mAb (A26561, 5 μl/Test, right).

Overview

Product name	PE Rabbit anti-Human MRC2 mAb
Catalog No.	A26561
Host species	Rabbit
Purification method	Affinity purification
Isotype	IgG
CloneNo.	ARC66230-PE

Background

This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease.

Immunogen information

Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 35-513 of human MRC2 (NP_006030.2).
Sequence	DAALPEPNVFLIFSHGLQGCLEAQGGQVRVTPACNTSLPAQRWKWVSRNRLFNLGTMQCLGTGWPGTNTTASLGMYECDREALNLRWHCRTLGDQLSLLLGARTSNISKPGTLERGDQTRSGQWRIYGSEEDLCALPYHEVYTIQGNSHGKPCTIPFKYDNQWFHGCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDNPSEENCGVIRTESSGGWQNRDCSIALPYVCKKKPNATAEPTPPDRWANVKVECEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPEGRWNDSPCNQSLPSICKKAGQLSQG
Gene ID
Swiss Prot
Synonyms	CD280; UPARAP; CLEC13E; ENDO180
Calculated MW	167kDa
Observed MW

Applications

Reactivity	Human
Tested applications	WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP Inhibition
Recommended dilution	FC 5 μl per 10^6 cells in 100 μl volume
Storage buffer	Store at 2-8℃. Avoid freeze. Buffer: PBS with 0.09% Sodium azide, 0.2% BSA, pH7.3.
Key application	Flow Cytometry
Positive samples
Cellular location	Membrane, Single-pass type I membrane protein, focal adhesion.

Documents

Certificate of Compliance

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Lot number

Research Area

연구면역학 & 염증CDs

PE Rabbit anti-Human MRC2 mAb images

Flow CytoMetry - PE Rabbit anti-Human MRC2 mAb (A26561)

Flow cytometry: 1X10^6 U-138MG cells were surface-stained with PE Rabbit IgG isotype control (A24172, 5 μl/Test, left) or PE Rabbit anti-Human MRC2 mAb (A26561, 5 μl/Test, right).

* For research use only. Not for therapeutic or diagnostic purposes.