Phospho-KSR1-S392 Rabbit pAb (AP0487)

Datasheet

Tested applications:WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP InhibitionReactivity:Human, Mouse, Rat

Overview

Product name	Phospho-KSR1-S392 Rabbit pAb
Catalog No.	AP0487
Host species	Rabbit
Purification method	Affinity purification
Isotype	IgG

Enables 14-3-3 protein binding activity; ATP binding activity; and protein C-terminus binding activity. Involved in positive regulation of MAPK cascade. Located in endoplasmic reticulum and membrane. Part of protein-containing complex. Implicated in breast adenocarcinoma. Biomarker of breast cancer.

Immunogen information

Immunogen	A synthetic phosphorylated peptide around S392 of human KSR1 (NP_001354739.1).
Sequence	RISFL
Gene ID
Swiss Prot
Synonyms	KSR; RSU2
Calculated MW	102kDa
Observed MW	Refer to figures

Applications

Reactivity	Human, Mouse, Rat
Tested applications	WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP Inhibition
Recommended dilution	WB 1:500 - 1:2000
Storage buffer	Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Key application	Western blotting
Positive samples
Cellular location	Cytoplasm, Endoplasmic reticulum membrane, Membrane, Peripheral membrane protein